SKIN BOOSTERS
Skin Boosters & Tissue Stimulators – What Are They and How Do They Work?
Skin boosters and tissue stimulators are modern injectable treatments used in aesthetic medicine to deeply hydrate, regenerate, and rejuvenate the skin from within. Unlike traditional fillers, they do not change facial features or add volume. Instead, they improve the overall quality of the skin, restoring its natural glow, elasticity, and firmness.
Skin Boosters – Deep Hydration and Skin Revitalisation
Skin boosters are formulations primarily based on stabilised hyaluronic acid. Their main goal is to enhance long-lasting hydration, replenish the skin’s natural HA levels, and improve tissue density.
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How do skin boosters work?
Once injected into the skin, they:
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attract and bind water to maintain high hydration levels,
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stimulate fibroblasts to produce collagen and elastin,
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improve skin smoothness and elasticity,
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reduce fine lines, roughness, and signs of fatigue.
Key active ingredients:
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non crossed hyaluronic acid,
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amino acids,
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biomimetic peptides,
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vitamins and antioxidants (depending on the formulation).
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sodium succinate (amber acid) – a powerful antioxidant that enhances cellular metabolism, improves microcirculation, and supports collagen synthesis.
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Visible effects:
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long-lasting hydration,
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brighter, more even skin tone,
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improved texture and elasticity,
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reduction of fine wrinkles.
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Tissue Stimulators – Regeneration and Skin Remodelling
Tissue stimulators are more advanced bioregenerative preparations designed to activate natural repair processes within the skin. They work deep in the dermis to stimulate cellular regeneration and rebuild structural support.
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How do tissue stimulators work?
After injection, they:
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activate fibroblasts to produce new collagen (type I and III),
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increase the synthesis of elastin,
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improve skin density and firmness,
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rebuild the dermal support matrix,
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provide lifting and tightening effects.
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Most common active ingredients:
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polynucleotides (PDRN) – strong tissue repair and regeneration,
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calcium hydroxyapatite – powerful collagen stimulation and skin thickening,
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poly-L-lactic acid (PLLA/PLA) – gradual biostimulation and lifting,
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amino acids and peptides – enhanced cellular activity,
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trehalose and antioxidants – protection and quality improvement of the skin.
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sodium succinate – enhances metabolic activity, improves oxygenation, and supports collagen remodeling.
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What Happens in the Skin After Skin Boosters or Tissue Stimulators?
Both skin boosters and tissue or collagen stimulators trigger a series of essential biological processes within the skin. They provide deep dermal hydration and initiate neocollagenesis, which is the formation of new collagen fibers, as well as neoelastogenesis, meaning increased elastin production. These treatments also enhance angiogenesis, improving microcirculation and oxygenation, while sodium succinate in particular boosts cellular metabolism. At the same time, the skin undergoes reorganisation of the extracellular matrix, and fibroblasts become more active, contributing to improved firmness, elasticity, and an overall more youthful appearance.
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As a result, the skin becomes:
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more elastic and firmer,
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deeply hydrated,
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brighter and more even,
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naturally rejuvenated and healthier.




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